Among the five most notable scientific breakthroughs of 2024, according to Le Soleil, is the remarkable discovery by Dr. Alexandre Caron’s team, one of our own researchers. Their work opens new chapters in the history of science with a major advancement: they may have uncovered the key behind the appetite-suppressing effects of Ozempic.
It was known that GLP-1 and molecules mimicking it could slow the transit of food through the digestive system, possibly also acting on the brain, and thus, it was thought, suppress hunger. Dr. Caron and his team discovered that the mechanism is far more complex and fascinating. They also identified new, previously unknown populations of neurons that play an important role in regulating appetite.
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Photo: Jocelyn riendeau, Le Soleil