According to Simon Duchesne, this neurodegenerative disease should be considered through the lens of overall brain health rather than the narrow prism of amyloid plaques.
The presence of amyloid plaques in the brain is increasingly imposed as the sole and unique diagnostic criterion for Alzheimer’s. The approval of new drugs that specifically target these amyloid protein accumulations could, despite their debatable effectiveness, draw even more attention to plaques—at the expense of a broader approach that integrates all the factors involved in the disease.
It is in response to this dominant trend in Alzheimer’s research that Simon Duchesne, professor at the Faculty of Medicine at Université Laval, and three of his colleagues have just published a reflective article in the Journal of Alzheimer’s Disease calling for a re-examination of our conception of the disease.
Ulaval Nouvelles: Click here to read the full article
